PHYSL 7910 - Practicum in Physiology

Taught alternate years. Required of majors; open to medical and graduate students. A laboratory-oriented practicum emphasizing the practice of physiological technique as it pertains to specific research problems. Course covers membrane models, ion selectivity, intracellular pH and calcium regulation. Recording surface potentials, ionic currents, nerve discharge and documentation of nervous activity with antibody markers are taught. The second half of the practicum empasizes assays involving antibodies including receptor binding, and radio immunoassays. Microfluorometric analysis, confocal microscopy, in-vivo drug assay, and genetic markers in disease are given practical consideration.